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MHRI-GHUCCTS Monthly Statistical Seminar Series 2022-2023

This free monthly webinar features Dr. Paul Kolm, Associate Director in the Department of Biostatistics and Biomedical Informatics at the MedStar Health Research Institute.

October 21 - Introduction to Statistics in Medical Research. We will discuss the use of statistics (and misuse) in medical research, what "statistical significance" means and what it does not mean.

November 18 - Comparative Effectiveness Analysis: Randomization and Pseudo-randomization. Randomized clinical trials are considered the gold standard of research design. Studies that are not randomized present a challenge to statistical analysis in that results can be biased due to confounding variables. We will look at methods that help to overcome bias.

December 16 - Linear and Nonlinear Regression Models. We will discuss regression models where the relationship between an outcome and one or more independent variables (covariates/predictors) is linear and where the relationship is nonlinear.

January 20 – Power and Sample Size: We will discuss considerations for determining the number of subjects/patients for a study as well as calculation of sample size.

February 17 – Logistic Regression: In this session we will discuss the analysis of categorical data that is binary, ordinal or nominal.

March 17 – Variable Selection for Predictive Models: There are a number of methods used for variable selection in regression models. We will examine the most common and compare with a more recent method, penalized regression.

April 21 – Cost-effectiveness Analysis: In many randomized or non-randomized clinical trials, cost-effectiveness has become a major part of treatment effectiveness. We will discuss methods and interpretation of CEA results.

May 19 – Meta-analysis: Meta analyses have become very common in the clinical literature and are often used to assess effect size and sample size for future studies. We will discuss traditional meta-analysis methods as well as the more recent use of network meta-a

You can choose to attend one or more of the following webinars.